Adolescent Medicine Trials Network V

 

The Adolescent Medicine Trials Network (ATN) for HIV Interventions was founded in 2001 and is the only HIV network exclusively focused on adolescents and young adults in the United States. The Institute on Digital Health and Innovation serves as the Scientific Leadership and Collaborations Center (SLC). The SLC will bring all elements of the network together and ensure that they function collaboratively, effectively, and efficiently with the Operations and Collaborations Center, NIH and the overall network. The SLC will also include a Statistical and Data Management Core (SDMC), which will provide expertise in study design, statistical analysis, data collection and data management.

The ATN will design, develop, and conduct clinical trials and implementation science research studies, and engaged youth participants into rigorously designed, collaborative protocols to address these high priority areas:

  1. Undiagnosed HIV infection: novel strategies to increase diagnosis
  2. Persistent new HIV infections: safety, PK/PD, acceptability and efficacy of novel biomedical HIV preventives
  3. Poor HIV care engagement: novel strategies to improve engagement in HIV care (eg, same day ART) that leverage collaborations with community and public health partners
  4. Poor ART adherence: safety, PK/PD, acceptability and efficacy of novel biomedical HIV treatments (including prevention)
  5. Adverse HIV health outcomes from COVID-19

The ATN will support an initial seven highly innovative and impactful clinical trials led by talented multidisciplinary teams, addressing NIH priority research areas, spanning key populations of youth, multiple socioecological systems, and a variety of regulatory phases. The ultimate goals of the ATN research portfolio include generating evidence and recommendations to advance the field of adolescent HIV medicine; influence clinical practice and protocols; reduce inequities in HIV-related outcomes; and inform community scale-up of sustainable, impactful biobehavioral interventions that reduce HIV transmission and improve individual outcomes for youth living with HIV.

Learn more about these research studies:

 

Visit the ATN Website